Induction of Glutathione S-Transferase in IGF Type I Receptor Overexpressed Hepatoma Cells
نویسندگان
چکیده
BK21 Project Team, College of Pharmacy, Chosun University, Gwangju 501-759, South Korea (J.Y.L., C.Y.H., J.W.Y., K.W.K.); Departments of Biological Chemistry/Developmental and Cell Biology, University of California at Irvine, CA, USA (E.Y.L., C.S.); College of Pharmacy and Research Center for Transgenic Cloned Pigs, Chungnam National University, Daejeon, 305-764, South Korea (S.K.K.); College of Pharmacy, Seoul National University, Seoul 151-742, South Korea (S.G.K.) Molecular Pharmacology Fast Forward. Published on July 5, 2007 as doi:10.1124/mol.107.038174
منابع مشابه
Induction of glutathione transferase in insulin-like growth factor type I receptor-overexpressed hepatoma cells.
Insulin-like growth factor type I receptor (IGF-IR) is frequently overexpressed in human hepatocellular carcinoma cells (HCC), and this overexpression has been correlated with increased tumor growth. The protective response of HCC to reactive oxygen species (ROS) produced by chemotherapeutic agents is mediated with the induction of phase II detoxifying genes including glutathione transferase (G...
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